Merlin Lopus

Post Doctoral Fellow

Dr. Merlin Lopus is working as Post Doctoral Fellow at CAbC- MSSRF with KSCSTE fellowship. She has completed B. Tech in Biomedical Engineering, M. Tech in Bioinformatics and received Doctorate in Bioinformatics. Her major research area is computational structural biology. She has identified structural changes and altered dynamic behavior of four oncogenes upon mutation. Currently she is working in Agriculture Bioinformatics and analyzing the drought and flood tolerant rice varieties of Wayanad. Genomic and proteomic analysis of drought and flood tolerant genes and its expression analysis in traditional rice varieties are being studied. She worked as Assistant professor for a period of 6 years in engineering colleges at Chennai and Thrissur. She also worked as Research Associate in Proteomics at Center for Bioseparation Technology, Vellore. Key publications:

Merlin Lopus, D. Meshach Paul and R. Rajasekaran (2016). Unraveling the Deleterious Effects of Cancer Driven STK11 Mutants Through Conformational Sampling Approach,Cancer Informatics, Vol. 15, pp. 35-44.

Tomy, Prajeesh; Lopus, Merlin; Rajasekaran, R. (2018). Identifying the Deleterious Effects of Cancer Driven Mad1, BRAF and STK11 Mutants Through Conformational Sampling Approach,  Journal of Bionanoscience, Volume 12, Number 1, pp. 109-118(10)

Merlin Lopus and R. Rajasekaran (2014). Exploring the Missense Mutation Impact on STK11 which Cause Peutz-Jeghers Syndrome by Computational Analysis, International Journal of ChemTech Research, Vol.6, No.2, pp 1251-1267.

Merlin Lopus and R. Rajasekaran (2013). In silico Analysis of Detrimental Missense Mutations in P110 α that Cause Cancer,Journal of Bionanoscience ,Vol. 7, pp. 1–8.

Merlin Lopus, P. Chandrasekaran, K. Sreevishnupriya, R. Rajasekaran, K. Ramanathan and V.A. Shanthi (2013). Computational Approach to Explore the Functional Missense Mutations in the Spindle Check Point Protein Mad1, Frontiers in Biology, Vol. 8, No.6, pp. 618-625.

Jagannathan, Merlin Lopus, Kukku Thomas (2014). Ambulatory Wireless Monitoring of Tremors in Patients with Parkinson’s Disease, Middle East Journal of Scientific Research, Vol. 20 Issue 12, p1894.